Bronchial Epithelial Cells: The Key Effector Cells in the Pathogenesis of Chronic Obstructive Pulmonary Disease?|
The authors discuss the abnormal function of bronchial epithelial cells within a disturbed immune homeostatic environment consisting of ongoing inflammation, oxidative stress and small airway obstruction. They provide an overview of recent insights into the function of the bronchial epithelium in the pathogenesis of chronic obstructive pulmonary disease and how this may provide novel therapeutic approaches for a number of chronic lung diseases. [Respirology]
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